tailieunhanh - Báo cáo y học: " Vancomycin-induced thrombocytopenia in a 60-year-old man: a case repor"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Vancomycin-induced thrombocytopenia in a 60-year-old man: a case repor | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report Vancomycin-induced thrombocytopenia in a 60-year-old man a case report Ravish A Shah Adnan Musthaq and Nancy Khardori Address Division of Infectious Diseases Department of Internal Medicine Southern Illinois University School of Medicine Springfield IL USA Email RAS - ravish1982@ AM - amusthaq@ NK - nkhardori@ Corresponding author Received 10 April 2008 Accepted 22 January 2009 Published 26 June 2009 Journal ofMedical Case Reports 2009 3 7290 doi 1752-1947-3-7290 This article is available from http jmedicalcasereports article view 7290 2009 Shah et al licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Vancomycin a glycopeptide antibiotic is used to treat resistant gram-positive infections. There has been a 10- to 20-fold increase in its use over the past 25 years. Although ototoxicity and nephrotoxicity are well known side effects of vancomycin it can also induce platelet reactive antibodies leading to life-threatening thrombocytopenia. Vancomycin is often clinically overlooked as a cause of thrombocytopenia especially in a scenario of sepsis or when there is use of heparin. We report a proven case of vancomycin-induced thrombocytopenia and its reversal after discontinuation of vancomycin. Case presentation A 60-year-old man with a history of hypertension congestive heart failure and dyslipidemia was admitted for a right shoulder rotator cuff tear. He underwent right-shoulder arthroscopy and rotator cuff repair. About three weeks later he developed pain swelling and purulent drainage from his right shoulder. Arthroscopic irrigation and drainage was then performed. Intraoperative fluid .