tailieunhanh - Báo cáo y học: " Hypertensive crisis-induced electrocardiographic changes: a case series"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Hypertensive crisis-induced electrocardiographic changes: a case series | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report Hypertensive crisis-induced electrocardiographic changes a case series Khalid Abou Farha1 André van Vliet1 Sjoerd van Marle1 Patrick Vrijlandt1 and Daan Westenbrink2 Addresses 1PRA-International Institute for Clinical Pharmacology Groningen and Zuidlaren The Netherlands 2Cardiology Department University Medical Centre Groningen The Netherlands Email KAF - AboufarhaKhalid@ AvV - VlietAndrevan@ SvM - MarleSjoerdvan@ PV - VrijlandtPatrick@ DW - bdwestenbrink@ Corresponding author Received 19 August 2008 Accepted 9 February 2009 Published 20 August 2009 Journal of Medical Case Reports 2009 3 7283 doi 1752-1947-3-7283 This article is available from http jmedicalcasereports article view 7283 2009 Farha et al. licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Myocardial injury is one of the most notorious complications of a hypertensive crisis. Key electrocardiograph signs used to detect cardiac injury such as ST segment changes and cardiac arrhythmias usually indicate acute ongoing end-organ damage. Lack of early signs to predict end-organ damage might lead to a delay in the initiation of therapy and selection of the incorrect therapeutic strategy. Case presentation We describe five cases of tall hyper acute symmetrical T-waves alone or accompanied by other electrocardiograph abnormalities in five healthy participants three women aged 52 60 and 62-years and two men aged 49 and 66-years during a tyramine-monoamine oxidase-inhibitor interaction phase I clinical trial. T-wave changes appeared early during the course of the hypertensive crisis and were attributed to .