tailieunhanh - Báo cáo y học: " Progressive visceral leishmaniasis misdiagnosed as cirrhosis of the liver: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Progressive visceral leishmaniasis misdiagnosed as cirrhosis of the liver: a case report | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report Progressive visceral leishmaniasis misdiagnosed as cirrhosis of the liver a case report Lydia Giannitrapani1 Maurizio Soresi1 Emanuele La Spada1 Claudio Tripodo2 and Giuseppe Montalto1 Address department of Clinical Medicine and Emerging Pathologies University of Palermo via del Vespro 141 90127 Palermo Italy and department of Human Pathology University of Palermo via del Vespro 129 90127 Palermo Italy Email LG - lydiagiannitp@ MS - soresi@ ELS - elas1976@ CT - tripodo@ GM - gmontal@ Corresponding author Received 18 January 2008 Accepted 23 January 2009 Published 25 June 2009 Journal ofMedical Case Reports 2009 3 7265 doi 1752-1947-3-7265 This article is available from http jmedicalcasereports article view 7265 2009 Giannitrapani et al licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Visceral leishmaniasis is a potentially life-threatening infectious disease which is caused by parasites of the genus Leishmania and characterized in most cases by the presence of fever as well as signs and symptoms similar to those found in liver cirrhosis. Case presentation In this case report we describe the history of a 50-year-old Caucasian man incorrectly diagnosed as having hepatitis C virus-associated liver cirrhosis with a massive weight loss of around 100 kg during the previous 2 years. However suspecting a lymphoproliferative disorder we were able to make a correct diagnosis of visceral leishmaniasis by bone marrow examination. After a course of therapy with Liposomal Amphotericin-B the patient recovered and now 20 months post-treatment he is well and has regained a good part of the