tailieunhanh - Báo cáo y học: "Primary biliary cirrhosis presenting with ascites and a hepatic hydrothorax: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Primary biliary cirrhosis presenting with ascites and a hepatic hydrothorax: a case report | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report Primary biliary cirrhosis presenting with ascites and a hepatic hydrothorax a case report Thomas George Wojcikiewicz and Sachin Gupta Address Department of Gastroenterology Princess Alexandra Hospital Harlow Essex UK Email TGW - tgwojcikiewicz@ SG - sachindr@ Corresponding author Received 9 November 2008 Accepted 29 January 2009 Published 14 July 2009 Journal ofMedical Case Reports 2009 3 7371 doi 1752-1947-3-7371 This article is available from http jmedicalcasereports article view 7371 2009 Wojcikiewicz and Gupta licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction We report an unusual presentation of primary biliary cirrhosis. Case presentation We present the case of a 66-year-old white British woman who presented to the Accident and Emergency department with ascites and unilateral pleural effusion hepatic hydrothorax . Following a liver biopsy the diagnosis of primary biliary cirrhosis was made. Conclusion It is important to consider the diagnosis of hepatic cirrhosis when presented with a unilateral pleural effusion in both the presence and absence of ascites. Introduction Primary biliary cirrhosis PBC occurs when interlobular bile ducts are damaged by chronic granulomatous inflammation. This causes progressive cholestasis cirrhosis and portal hypertension. Often asymptomatic diagnosis usually comes about following the discovery of a raised alkaline phosphatase on routine liver function tests LFTs . Symptoms include lethargy and pruritis. Clinical signs include jaundice skin pigmentation xanthelasma xanthomata hepatomegaly and splenomegaly. Complications of the disease include osteoporosis .