tailieunhanh - Báo cáo y học: "Fixed drug eruption resulting from fluconazole use: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Fixed drug eruption resulting from fluconazole use: a case report | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report Fixed drug eruption resulting from fluconazole use a case report Mahkam Tavallaee1 and Mahnaz Mahmoudi Rad2 Addresses department of Health Sciences Simon Fraser University Burnaby Canada V5A 1S6 and 2Skin Research Center Shaheed Beheshti University of Medical Sciences and Health Services Tehran Iran Email MT - mtavalla@ MMR - mahnazrad@ Corresponding author Received 27 November 2008 Accepted 29 January 2009 Published 6 July 2009 Journal ofMedical Case Reports 2009 3 7368 doi 1752-1947-3-7368 This article is available from http jmedicalcasereports article view 7368 2009 Tavallaee and Rad licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Fluconazole is a widely used antifungal agent with a possible side effect of fixed drug eruption. However this adverse drug effect is absent from the reported list of possible side effects of fluconazole. We are presenting a rare case in our report. Case presentation A 25-year-old Iranian woman developed fixed drug eruptions on different sites of her body after taking five doses of fluconazole to treat vaginal candidiasis. A positive patch test positive oral challenge test and skin biopsy were all found to be consistent with fixed drug eruption. Conclusion Fluconazole is a widely prescribed drug used mainly to treat candidiasis. Fixed drug eruption as a possible side effect of Fluconazole is not well known and thus the lesions may be misdiagnosed and mistreated. Based on our findings which are consistent with a number of other practitioners we recommend adding fixed drug eruption to the list of possible side effects of fluconazole. Introduction Fluconazole Diflucan is a