tailieunhanh - Báo cáo y học: "Osteoradionecrosis of the cervical spine presenting with quadriplegia in a patient previously treated with radiotherapy for laryngeal cancer: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Osteoradionecrosis of the cervical spine presenting with quadriplegia in a patient previously treated with radiotherapy for laryngeal cancer: a case report | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report Osteoradionecrosis of the cervical spine presenting with quadriplegia in a patient previously treated with radiotherapy for laryngeal cancer a case report Frederik Carl van Wyk Manu-priya Sharma and Robert Tranter Address Department of Otolaryngology and Head and Neck Surgery Brighton and Sussex University Hospitals NHS Trust Eastern Road Brighton UK Email FCVW - fcvanwyk@ MS - mpns@ RT - rtranter@ Corresponding author Received 28 July 2007 Accepted 29 January 2009 Published 10 June 2009 Journal ofMedical Case Reports 2009 3 7262 doi 1752-1947-3-7262 This article is available from http jmedicalcasereports article view 7262 2009 van Wyk et al licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Osteoradionecrosis of the mandible and temporal bones has been extensively reported in literature but cases of avascular necrosis of the cervical spine following radiotherapy to the larynx appear to be extremely rare. A review of the English language literature has shown only one other case where radiotherapy treatment of a laryngeal carcinoma has resulted in osteoradionecrosis of the cervical spine. Case presentation We present the case of a 65 year old male patient who suffered from osteoradionecrosis of the cervical spine 20 years after radiotherapy treatment for a T1aN0M0 laryngeal carcinoma resulting in quadriplegia. Conclusions Radiotherapy carries a long-term risk of complications including osteoradionecrosis which may present 20 years later with significant implications. Introduction Osteoradionecrosis is defined as necrosis of the bone following irradiation 1 . It was first .