tailieunhanh - Biochemistry, 4th Edition P111

Biochemistry, 4th Edition P111. Continuing Garrett and Grisham's innovative conceptual and organizing framework, "Essential Questions," BIOCHEMISTRY guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. Streamlined for increased clarity and readability, this edition also includes new photos and illustrations that show the subject matter consistently throughout the text. New end-of-chapter problems, MCAT practice questions, and the unparalleled text/media integration with the power of CengageNOW round out this exceptional package, giving you the tools you need to both master course concepts and develop critical problem-solving skills you can draw upon. | Abbreviated Answers to Problems A-3 6. a. Keq AC X 1000 20. b. AG AB kJ mol. AG BC kJ mol. AG AC kJ mol. Keq 20. 7. See The Student Solutions Manual Study Guide and Problems Book for resonance structures. 8. Keq Cr P1 CrP H2O . Keq X 107. 9. CrP 1n the amount of moles would be required per day to provide 5860 kJ energy. This corresponds to 17 730 g of CrP per day. With a body content of 20 g CrP each molecule would recycle 886 times per day. Similarly 637 moles of glycerol-3-P or 108 300 g of glycerol-3-P would be required. Each molecule would recycle 5410 times day. 10. AG kJ mol. 11. The hexokinase reaction is a sum of the reactions for hydrolysis of ATP and phosphorylation of glucose ATP H2O -- ADP Pi Glucose Pi -- G-6-P H2O Glucose ATP -- G-6-P ADP The free energy change for the hexokinase reaction can thus be obtained by summing the free energy changes for the first two reactions listed here. AG for hexokinase kJ mol kJ mol kJ mol 12. Comparing the acetyl group of acetoacetyl-CoA and the methyl group of acetyl-CoA it is reasonable to suggest that the acetyl group is more electron-withdrawing in nature. For this reason it tends to destabilize the thiol ester of acetoacetyl-CoA and the free energy of hydrolysis of acetoacetyl-CoA should be somewhat larger than that of acetyl-CoA. In fact AG kJ mol compared with kJ mol for acetyl-CoA. 13. Carbamoyl phosphate should have a somewhat larger free energy of hydrolysis than acetyl phosphate at least in part because of greater opportunities for resonance stabilization in the products. In fact the free energy of hydrolysis of carbamoyl phosphate is kJ mol compared with kJ mol for acetyl phosphate. 14. The denaturation of chymotrypsinogen is spontaneous at 58 C because the A G at this temperature is negative at approximately kJ mol . The native and denatured forms are in equilibrium at approximately C. 15. The positive values for ACp for .