tailieunhanh - Pharmaceutical Substances Syntheses, Patents, Applications - Part 130

Pharmaceutical Substances Syntheses, Patents, Applications - Part 130. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Methoxyflurane M 1291 Methoxyflurane ATC N01AB03 Use inhalation anesthetic RN 76-38-0 MF C3H4C12F2O MW EINECS 200-956-0 LD 0 150 mg kg M . 3600 mg kg R . CN 2 2-dichloro-1 1 -difluoro-1 -methoxyethane F KOH CI C- F 1 1 -difluoro- 2 2 2-trichloro- ethone H3C OH KOH --------- Methoxyflurane 1 1 -dichloro-2 2-difluoro-ethylene Reference s GB 928 786 Dow appl. USA-prior. . Formulations sol. 125 mg 125 ml Trade Name s D Penthrane Abbott wfm I Pentrane Abbott wfm USA Penthrane Abbott wfm GB Penthrane Abbott wfm J Penthrane Abbott Methscopolamine bromide Hyoscine methobromide ATC A03 Use parasympatholytic antispasmodic RN 155-41-9 MF C18H24BrNO4 MW EINECS 205-844-5 LD50 mg kg M . 619 mg kg M . mg kg R i. V. 3400 mg kg R . CN 7 S - la 2ß 4ß 5a 7ß -7- 3-hydroxy-l-oxo-2-phenylpropoxy -9 9-dimethyl-3-oxa-9-azoniatricyclo 4 nonane bromide nitrate RN 6106-46-3 MF C18H24N2O7 MW EINECS 228-065-2 methylsulfate RN 18067 13-5 MF C18H24NO4 CH3SO4 MW EINECS 241-975-4 scopolamine q. V. Br CH-J methyl bromide 1292 M Methyclothiazide Methscopolamine bromide AgNO-j ------ NOJ methscopolomine nitrate Reference s DE 145 996 E. Merck AG appl. 1902 . US 2 753 288 Upjohn 1956 prior. 1952 . Formulation s cps. mg syrup mg 5 ml tabl. mg Trade Name s D Holopon Byk Gulden Oragallin s Hormon- GB Famine Upjohn wfm wfm Chemie -comb. wfm Skopyl Farillon wfm Ichtho-Spasmin Ichthyol - Skopyl Pharmacia as J Ace Ono comb. wfm nitrate wfm Meporamin Taiyo Methyscopolamin Spasmo-Bilicura Mueller USA Pamine Upjohn wfm Upjohn wfm Goppingen -comb. wfm Methyclothiazide ATC CO3AAO8 Use diuretic RN 135-07-9 MF MW EINECS 205-172-2 LD50 400 mg kg M . 10 g kg M . 4 g kg R . CN 6-chloro-3- chloromethyl 3 4-dihydro-2-methyl-2 7-l 2 4-benzothiadiazine-7-sulfonamide 1 1-dioxide 5-ch1oro-2 4-di-sulfamoylaniline . 1 . h2n nh2 180 C - HjC I DMF. NaH J urea 7-sulïomoyl-6-chioro-3- 0X0-3 .