tailieunhanh - Pharmaceutical Substances Syntheses, Patents, Applications - Part 200

Pharmaceutical Substances Syntheses, Patents, Applications - Part 200. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Terbinafine T 1991 process for a polymorph CA2 173 407 Acic appl. . WO9 721 705 Uetikon appl. D-prior. . US 5 587 377 Invamed USA-prior. . capsules WO9 805 308 Novartis appl. USA-prior. . pharmaceutical composition for treating glaucoma WO9 531 200 Senju Pharm. appl. J-prior. . tf - -terazosin WO9 200 073 Abbott appl. USA-prior. . Formulation s cps. USA 1 mg 2 mg 5 mg 10 mg tabl. 1 mg 2 mg 5 mg 10 mg as monohydrochloride dihydrate Trade Name s D Flotrin Í Flotrin Start Abbott Heitrin Abbott 1985 Dysalfa Débat Hytrine Abbott GB Hytrin Abbott 1987 J Hytracin Dainabot Vasomet Mitsubishi USA Hytrine Abbott 1987 Terbinafine SF-86327 ATC D01AE15 D01BA02 J02AX Use orally and topically active antifungal RN 91161-71-6 MF C21H25N MW LD50 393 mg kg M . 4000 mg kg M . 2 g kg M . 213 mg kg R . 4000 mg kg R . 2 g kg R . 2 g kg R skin CN -Ar- 6 6-dimethyl 2-hepten-4-ynyl -7V-methyl-l-naphthalenemethanamine hydrochloride RN 78628-80-5 MF C21H25N HC1 MW LD50 2 g kg M . 2 g kg R . 2 g kg R skin CH3 h2c cho 4- HC C- CH3 ch3 C H9Li butyllithium -en-4-yn 3-ol acrolein tert-butyl-acetylene H 3 CH3 CH3 1. Na2C03 2. isolation of the 1 -bromo-6 6-dirnethyl-hept-2-en-4-yne 1 1 -naphthyl-methyl methyl-omine trans isomer Terbinofine Reference s EP 24 587 Sandoz appl. CH-prior. . Stütz A. Petranyi G. J. Med. Chem. JMCMAR 27 1539 1984 . 1992 T Terbutaline Formulation s cream 10 mg g tabl. 250 mg as hydrochloride Trade Name s D Lamisil Novartis 1991 F Lamisil Novartis GB Lamisil Novartis 1990 I Daskil LPB Lamisil Novartis J Lamisil Toko Yakuhin- Sandoz USA Lamisil Novartis Terbutaline ATC RO3ACO3 RO3CCO3 Use bronchodilator tocolytic RN 23031-25-6 MF C12H19NO3 MW EINECS 245-385-8 CN 5- 2- l l-dimethylethyl amino -l-hydroxyethyl -l 3-benzenediol sulfate 2 1 RN 23031-32-5 MF C12H1S NO3 1 2H2SO4 MW EINECS .

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