tailieunhanh - Pharmaceutical Substances Syntheses, Patents, Applications - Part 20

Pharmaceutical Substances Syntheses, Patents, Applications - Part 20. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Bendacort B 191 Trade Name s D Card-Fludilat Thiemann - comb. with digoxin Fludilat Thiemann F Novo-Card-Fludilat Thiemann -comb. Fludilat Organon wfm I Angiociclan Organon Italia J Halidor Sumitomo as fumarate Bendacort Bendacortone ATC D07XA Use glucocorticoid RN 53716-43-1 MF C37H42N2O7 MW EINECS 258-710-3 CN llp -l 1 17-dihydroxy-21- l- phenylmethyl -lH-indazol-3-yl oxy acetyl oxy pregn-4-ene-3 20-dione hydrocortisone q. bendazolic acid chloride q. v. bendazac Referenced s DOS 2 601 367 Angelini appl. I-prior. . Formulation s cream 3 ointment 3 Trade Name s I Versacort Angelini Bendazac Bindazac Acido bendazolico ATC M02AA11 S01BC07 Use anti-inflammatory RN 20187-55-7 MF C16H14N2O3 MW EINECS 243-569-2 LD50 380 mg kg M . 1105 mg kg M . 304 mg kg R . 1200 mg kg R . CN l- phenylmcthyl -1 7-indazol-3-yl oxy acetic acid sodium salt RN 23255-99-4 MF Ci6H13N2NaO3 MW EINECS 245-528-4 1 -benzyl-3-hydroxy-1H-indazole 1. KOH 2. Br COOH 1. potassium hydroxide 2. bromoacetic acid COOH Bendazac 192 B B endroflume thiazide Reference s US 3 470 194 Angelini Francesco I-prior. . starting material Palazzo G. et al. J. Med. Chem. JMCMAR 9 38 1966 . use in ointments lotions etc. US 3 470 298 Angelini Francesco prior. . Bendacort q. v. Formulation s cream 1 3 ointment 1 3 Trade Name s I Bendaline Angelini - Versus Angelini comb with lysine J Zildasac Chugai Bendroflumethiazide Bendrofluazide ATC C03AA01 Use diuretic antihypertensive RN 73-48-3 MF C15H14F3N3O4S2 MW EINECS 200-800-1 LD50 395 mg kg M . 10 g kg M . . CN 3 4-dihydro-3- phenylmethyl -6- trifluoromethyl -2H-l 2 4-benzothiadiazine-7-sulfonamide 1 1-dioxide Sx. J b. 0 sIH2 sf 2 V J A 0 nh2 0 3-trifluoromethyl- niline 4-omino-6-trifluoro-methyl-1 3-benzene-disulfochloride 2 4-diominosulfonyl- 5-trifluoromethyloniline I phenylacetyl chloride Bendroflumethiazide 0-ethoxystyrene .

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