tailieunhanh - Pharmaceutical Substances Syntheses, Patents, Applications - Part 81

Pharmaceutical Substances Syntheses, Patents, Applications - Part 81. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Ethoheptazine E 801 Oophormin Luteum Teikoku Zoki USA Duosterone Roussel - comb. wfm Ora-Lutin Parke Davis wfm Prodroxan Dorsey wfm Progestab Beecham wfm Progestoral Organon wfm Syngestrotabs Pfizer wfm Trosinone Abbott wfm Ethoheptazine ATC N02A Use analgesic RN 77-15-6 MF C16H23NO2 MW EINECS 201-007-3 LD50 65 mg kg M . 318 mg kg M . 34 mg kg R . 355 mg kg R . CN hexahydro-l-methyl-4-phenyl-lH-azepine-4-carboxylie acid ethyl ester citrate 1 1 RN 6700-56-7 MF C 6H23NO2 C6H8O7 MW EINECS 229-743-0 LDS0 580 mg kg R . 1. NoNH2 phenyloceta-nitrile 1. sodium amide 4-dimethylamino- 2-phenylbutyronitrile 1. NoNH2 2. Br Br -------- ------- I 1. 1 3-dibromo- propone 2. 2- dimethylami-no ethyl chloride 4-cyano-1 -methyl-4-phenylhexahydro-azepine II Reference s US 2 666 050 American Home Products 1954 prior. 1952 . Formulation s tabl. 75 mg in comb. Trade Name sj GB Equagesic Wyeth -comb. I Panalgin Padil wfm J combination preparations wfm Zactirin Banyu -comb. USA Equagesic Wyeth wfm Mepro Schein wfm Zactane Wyeth wfm 802 E Ethos uximide Zactirin Wyeth wfm Ethosuximide ATC N03AD01 Use antiepileptic antiparkinsonian RN 77-67-8 MF C7H11NO2 MW EINECS 201-048-7 LD50 780 mg kg M . 1530 mg kg M . CN 3-ethyl-3-methyl-2 5-pyrrolidinedione ethyl cyonoocetate butanone piperidine 2--------- H2S04 ÇOOH HOOC CH CH3 0 0 NH 2-ethyl-2-methyl succinic acid Reference s US 2 993 835 Parke Davis prior. . Sahay s. Sircar G. J. Chem. Soc. JCSOA9 1927 1252. Fomulation s cps. 250 mg sol. 50 g 100 g syrup 250 mg 5 ml Trade Name s D Petnidan Desitin Zarontin Parke Davis I Zarontin Parke Davis J Emeside Technish- Kodama Epileo Petitmal Eisai Zarontin Parke Davis-Sankyo USA Zarontin Parke Davis Suxilep Jenapharm Suxinutin Parke Davis F Zarontin Parke Davis GB Emeside Labs for Applied Biology Ethotoin ATC N03AB01 Aethotoin ưse RN 86-35-1 MF CnH12N2O2 MW EINECS 201-665-1 LD5 1750 mg kg M . 1500 mg kg R . CN 3-ethyI-5-phenyl-2 .