tailieunhanh - Pharmaceutical Substances Syntheses, Patents, Applications - Part 61

Pharmaceutical Substances Syntheses, Patents, Applications - Part 61. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Desoxycortone acetate D 601 0 30-hydroxy-2O-oxo-5 16- formic pregnodiene 1 acid from diosgenin JI h3c ok IV h3c-co-ch3 Desoxycortone acetate VI 602 D Detajmium bitartrate ai och ch3 2 cyclo- aluminum hexanone triisopropylate Desoxycortone acetate Reference s a Sondheimer F. et al. J. Am. Chem. Soc. JACSAT 79 5034 1957 . synthesis of I Wall . J. Am. Chem. Soc. JACSAT 77 5665 1955 . b Ringold . Stork G. J. Am. Chem. Soc. JACSAT 80 250 1958 . c Ruschig H. Angew. Chem. ANCEAD 60 247 1948 . Ruschig H. Chem. Ber. CHBEAM 88 878 1955 . alternative syntheses DE 871 153 Hoechst appl. 1937 . DE 875 353 Schering AG appl. 1938 . US 2 312 480 Roche-Organon 1943 CH-prior. 1937 . US 2 409 043 Schering Corp. 1946 D-prior. 1939 . US 2 470 903 W. c. Ross 1949 GB-prior. 1945 . Serini A. et al. Ber. Dtsch. Chem. Ges. BDCGAS 72 391 1939 . Wilds A L. Shunk . J. Am. Chem. Soc. JACSAT 70 2427 1948 . review Ullmanns Encykl. Tech. Chem. 4. Aufl. Vol. 13 52. Formulation s amp. 10mg ml Trade Name s D Docabolin Nourypharma as phenylpropionatc- comb. wfm F Syncortyl Roussel Diamant GB Percorten M Crystals Ciba as pivalate wfm I Cortiron Schering wfm Neodin Lusofarmaco wfm Sinsurrene Parke Davis -comb. wfm J Syncorta Takeda USA Doca Acetate Organon wfm Percorten Ciba wfm Detajmium bitartrate ATC co IB Use antiarrhythmic RN 53862-81-0 MF C27H42N3O3 C4H6O6 H2O MW LD5o 6000 Rg kg R . CN 17R 21a -4- 3- diethylamino -2-hydroxypropyl -17 21-dihydroxyajmalanium salt with R R R -2 3-dihydroxybutanedioic acid 1 1 monohydrate tartrate 1 1 RN 33774-52-6 MF C27H42N3O3 C4H6O6 MW LD50 10 mg kg R . 290 mg kg R . Cl ch3 epichlorohydrin diethylamine OH ci- A .n ch3 NaOH 0 I -CHs ÁKJkxCH3 1 diethylamino- 2 3-epoxypropane I r Dexamethasone D 603 Reference s DE 2025 286 VEB Arzneimittelwerk Dresden appL DDR-prior. . GB 1 244 597 VEB Arzneimittelwerk Dresden appl. DDR-prior. . Formulation s sugar coated tabl. 25 mg Trade Name s D Tachmalcor ASTA .