tailieunhanh - Pharmaceutical Substances Syntheses, Patents, Applications - Part 47

Pharmaceutical Substances Syntheses, Patents, Applications - Part 47. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Cicletanine c 461 J1 Cicletanine Ị Cycletanide ATC CO3BXO3 Use diuretic antihypertensive RN 89943-82-8 MF C14H12C1NO2 MW LD50 4500 mg kg M . 5000 mg kg R . CN -3- 4-chlorophenyl -l 3-dihydro-6-methylfuro 3 4-c pyridin-7-ol hydrochloride RN 82747-56-6 MF C14H12C1NO2 HC1 MW pyridoxine acetone q- HCI - HjC CHj oxo CrO3 pyridine or MnO2 ------------------------ 1 3 4a-0-iso-propylidene-pyridoxine chromium trioxide or manganese dioxide 2 2 8-trimethyl-5- formyl-4H-pyrido- BrMg 4-chlorophenyl-mognesium Cl 3 4-d -1 3-dioxone 1 bromide Reference s DOS 3 204 596 Soc. de Conseils de Recherche et d Appl. Sei. appl. GB-prior. . US 4 383 998 Soc. de Conseils de Recherche et d Appl. Sei. GB-prior. . synthesis ớ 2 2 8-trimethyl-5-formyl-4Z -pyrido 3 4-ifl-l 3-dioxane Koryntyk W Wiedemann w. J. Org. Chem. JOCEAH 27 2531 1962 . Koryntyk W Kris . Singh . J. Org. Chem. JOCEAH 29 574 1964 . Sattsangi . Argoudelis . J. Org. Chem. JOCEAH 33 1337 1968 . Formulation s cps. 50 mg 100 mg hydrochloride Trade Name s D Justar Intersan 1989 F Ciclometasone Tenstaten Ipsen-Beaufour 1988 ATC D07AB H02AB Use glucocorticoid RN 86022-88-0 MF C32H44CINO7 MW EINECS 289-141-9 CN llß 16ß 21 trans -21- 4- acetylamino methyl cyclohexyl carbonyl oxy -9-chloro-l 1 17-dihydroxy-16-methylpregna-1 4-diene-3 20-dione 462 C Ciclonium bromide HOOC 1. pyridine HOOC CHj - S0CI tronexamic ocid q. v 0 cApi H 0 1 beclometasone q. v. 2 Reference s FR 2 280 384 Rorer appl. . synthesis q 4-aminomethylcyclohexanecarboxylic acid Levine M. Sedlecky R. J. Org. Chem. JOCEAH 24 115 1959 . Trade Name s I Cycloderm Rottapharm Telecort Sray Rottapharm Ciclonium bromide ATC A03DA04 Use antispasmodic anticholinergic RN 29546-59-6 MF C22H34BrNO MW EINECS 249-687-0 LD n 400 mg kg M . 1030 mg kg R . CN 2- 1 -bicyclo hept-5-en-2-yl-1 -phcnylethoxyj-A .iV-dicthyl-A -mcthylethanaminium bromide ocetophenone bicyclo .