tailieunhanh - Pharmaceutical Substances Syntheses, Patents, Applications - Part 36

Pharmaceutical Substances Syntheses, Patents, Applications - Part 36. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Carfecillin C 351 Carfecillin atc goiaaos joica Use antibiotic RN 27025-49-6 MF C23H22N2O6S MW EINECS 248-171-2 LD5n 728 mg kg M 3924 mg kg M . CN 2S- 2a 5a 6 -6- l 3-dioxo-3-phenoxy-2-phenylpropyl amino -3 3-dimethyl-7-oxo-4-thia-l- azabicyclo heptane-2-carboxylic acid phenyl malonic acid 0 ccon 6 monophenyl phenyl-malonote I COOH H2N 4 S ------------------------ 6-aminapenicillanic acid Reference s US 3 853 849 Beecham prior. and . US 3 881 013 Beecham GB-prior. and . Formulation s tabl. 500 mg Trade Name s I Uricillina IBI Urocarf SPA as sodium salt J Gripenin-O Fujisawa Uticillin SmithKline Beecham Carfenazine ATC nosak Carphenazine Use neurolePtic RN 2622-30-2 MF C24H31N3O2S MW EINECS 220-072-9 CN l- 10- 3- 4- 2-hydroxyethyl -l-piperazinyl propyl -10H-phenothiazin-2-yl -l-propanone dimaleate RN 2975-34-0 MF C24H31N3O2S 2C4H4O4 MW EINECS 221-019-2 LD50 42 mg kg M . 156 mg kg M . 162 mg kg R . 2-propionyl-phenothiozine 1. NaH 2. ------------- 1. sodium hydride 2. 1-bromo 3-chloropropane 10- 3-chlorapropyl -2-prapionylphenothiazine 1 352 c Carindacillin 1- 2-hydroxy-ethyl piperazine Reference s US 2 985 654 Schering Corp. 1961 appl. 1956 . US 3 023 146 American Home appl. prior. . Formulation s tabl. 25 mg 400 mg Trade Name s USA Proketazine Wyeth wfm Carindacillin ATC J01CA05 Indanylcarbenicilline Carbenicillin Indanyl Sodium Use antibiotic RN 35531-88-5 MF C26H2fiN2O6S MW LD5ü 3600 mg kg M . 2 g kg R . 500 mg kg dog . CN 2S- 2a 5a 6ß -6- 3- 2 3-dihydro-lH-inden-5-yl oxy -l 3-dioxo-2-phenylpropyl amino -3 3-dimethyl- 7-oxo-4-thia-l-azabicyclo heptane-2-carboxylic acid monosodium salt RN 26605-69-6 MF C26H25N2NaO6S MW EINECS 247-845-3 LD5 i 210 mg kg M . 4400 mg kg M . 295 mg kg R . 4450 mg kg R . mg kg dog . phenylmalonic PC s phosphorus pentachloride phenyl .

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