tailieunhanh - Pharmaceutical Coating Technology (Part 8)

Coating pans and coating columns Graham SUMMARY This chapter provides some examples of the type of equipment that is currently available. It is not exhaustive, but will highlight the main features that should be considered when evaluating and selecting appropriate units together with ancillary equipment for spraying and control of the coating process. CONVENTIONAL COATING PANS It is not proposed to discuss in detail the use of conventional coating pans as these are being phased out with the preference for more sophisticated pans and systems. Various methods have been used to improve the coating characteristics in this type. | Page 205 8 Coating pans and coating columns Graham SUMMARY This chapter provides some examples of the type of equipment that is currently available. It is not exhaustive but will highlight the main features that should be considered when evaluating and selecting appropriate units together with ancillary equipment for spraying and control of the coating process. CONVENTIONAL COATING PANS It is not proposed to discuss in detail the use of conventional coating pans as these are being phased out with the preference for more sophisticated pans and systems. Various methods have been used to improve the coating characteristics in this type of pan which was originally designed for sugar coating. Some examples are shown in Figs. - . The modifications made to sugar-coating pans were an attempt to utilize existing equipment and while successful for solvent-based film-coating systems they do not have the advantages of side-vented pans when aqueous film coats are applied. MANESTY ACCELACOTA The Accelacota is used as a model against which all other manufacturers units are compared. That is not intended to imply any preference but as a means of providing a road map through the maze of information available. The data quoted is intended as a guideline to indicate the range and size of the Accelacotas and the most suitable ancillary equipment available. Margins of safety Page 206 Fig. Standard coating pan. have been included to allow for a range of operating conditions. They should not be considered as specific nor should they be compared with other manufacturers quoted data. Where comparisons are to be made these should be related to the particular coating conditions. Like must be compared with like. Four sizes of Accelacota are available Model 10 operates with a batch size of 8-18 kg. Model 75 operates with a batch size of 40-90 kg. Model 350 operates with a batch size of 250-450 kg. Model 150 operates with a batch size of 80-180 kg. The essential .