tailieunhanh - Transcriptome sequencing reveals circRNA expression profile in Parkinson’s disease-like mice after aerobic exercise

This study aimed to explore whether EX acts on PD in mice mode. Mice were administered 1-methyl-4-phenyl1,2,3,6-tetrahydropyridine (MPTP) and subjected to a 4-week physical exercise regimen (EX-PD group) and underwent RNA-Seq. Here, MPTP caused PD, which was characterized by neuron shrinkage and behavioral deficits, whereas EX improved PD by rescuing neuronal survival and motor function in mice. |

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