tailieunhanh - Summary of medical doctoral dissertation: Assessment of treatment outcome of acute obstructive pyelonephritis due to ureteral calculi

To describe the clinical characteristics and paraclinical parameters in patients with acute obstructive pyelonephritis due to ureteral calculi; to evaluate the results of early treatment and somes risk factors predictive of septic shock in patients with acute obstructive pyelonephritis due to ureteral calculi | HUE UNIVERSITY UNIVERSITY OF MEDICINE AND PHARMACY LE DINH DAM ASSESSMENT OF TREATMENT OUTCOME OF ACUTE OBSTRUCTIVE PYELONEPHRITIS DUE TO URETERAL CALCULI SUMMARY OF MEDICAL DOCTORAL DISSERTATION HUE - 2022 The work is completed at University of Medicine and Pharmacy Hue University Academic supervisors Assoc. Prof. Nguyen Khoa Hung MD PhD Assoc. Prof. Nguyen Truong An MD PhD The dissertation can be found at 1. National Library of Vietnam 2. Library of University of Medicine and Pharmacy Hue University HUE UNIVERSITY UNIVERSITY OF MEDICINE AND PHARMACY LE DINH DAM ASSESSMENT OF TREATMENT OUTCOME OF ACUTE OBSTRUCTIVE PYELONEPHRITIS DUE TO URETERAL CALCULI MAJOR SURGERY CODE SUMMARY OF MEDICAL DOCTORAL DISSERTATION HUE - 2022 ABBREVIATIONS APN Acute pyelonephritis AUA American Urological Association BMI Body mass index BUN Blood urea nitrogen CI Confidence interval CRP C-reactive protein CT Computed Tomography EAU European Association of Urology eGFR estimated glomerular filtration rate OR Odds ratio PCT Procalcitonin SD Standard deviation TNF Tumor necrosis factor VUNA Vietnam Urology Nephrology Association WBC White blood cells INTRODUCTION Acute pyelonephritis APN is a severe upper urinary tract infection which refers to infection of the renal pelvis and the parenchyma 82 . APN is broadly divided into two groups uncomplicated and complicated. Complicated APN was defined as APN in patients who presented with any of the following conditions underlying functional or structural urologic abnormalities risk associated factors including diabetes mellitus or immunocompromised status 75 . Complicated APN with obstructive uropathy secondary to urinary calculi is not uncommon 174 . If acute obstructive pyelonephritis is not treated promptly and properly it can rapidly progress to serious conditions urosepsis and septic shock and death. Several series have shown that up ranged from 40 to 85 of those who develop urosepsis and shock had underlying obstruction 56 75 .