tailieunhanh - Genome-wide analyses reveal a role of Polycomb in promoting hypomethylation of DNA methylation valleys

Previous studies showed that the majority of developmental genes are devoid of DNA methylation at promoters even when they are repressed. Such hypomethylated regions at developmental genes are unusually large and extend well beyond proximal promoters, forming DNA methylation valleys (DMVs) or DNA methylation canyons. |

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