tailieunhanh - Lisa: Inferring transcriptional regulators through integrative modeling of public chromatin accessibility and ChIP-seq data

Based on the input gene sets, Lisa first uses histone mark ChIP-seq and chromatin accessibility profiles to construct a chromatin model related to the regulation of these genes. Using TR ChIP-seq peaks or imputed TR binding sites, Lisa probes the chromatin models using in silico deletion to find the most relevant TRs. |

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