tailieunhanh - Simultaneous determination of dexpanthenol, lidocaine hydrochloride, and mepyramine maleate in combined pharmaceutical gel by capillary electrophoresis

A new capillary electrophoresis method was developed for the simultaneous determination of dexpanthenol (DEX), lidocaine (LID), and mepyramine (MEP) in pharmaceutical preparations. The best results were obtained using 20 mM (pH ) phosphate buffer as the background electrolyte. Separation was obtained using a fused-silica capillary (75 µm internal diameter, 50 cm total length, 41 cm effective length) and a potential of +30 kV at 20 ◦ C. Standards and samples were injected using a pressure injection at 50 mbar for 5 s and the analytes were monitored at a detection wavelength of 200 nm. |

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