tailieunhanh - In-vitro antibacterial, antioxidant and cytotoxic potential of gold nanoparticles synthesized using novel Elaeocarpus ganitrus seeds extract

In the present study, we have follwed the hydrothermal path for the synthesis of gold nanoparticles (Au NPs) from the biomaterial Elaeocarpus ganitrus seeds extract, which is a rapid, eco-friendly, non-chemical way. The prepared NPs were thoroughly analysed by powder x-ray diffraction and high resolution transmission electron microscopy studies and were also tested for anticancer studies. | Journal of Science Advanced Materials and Devices 6 2021 127e133 Contents lists available at ScienceDirect Journal of Science Advanced Materials and Devices journal homepage locate jsamd Original Article In-vitro antibacterial antioxidant and cytotoxic potential of gold nanoparticles synthesized using novel Elaeocarpus ganitrus seeds extract . Vinay a Udayabhanu b . Sumedha b M. Shashank b G. Nagaraju b N. Chandrasekhar a a Research and Development Center Department of Chemistry Shridevi Institute of Engineering and Technology Tumakuru 572106 Karnataka India b Energy Materials Research Laboratory Department of Chemistry Siddaganga Institute of Technology Tumakuru 572103 Karnataka India a r t i c l e i n f o a b s t r a c t Article history In the present study we have follwed the hydrothermal path for the synthesis of gold nanoparticles Au Received 1 April 2020 NPs from the biomaterial Elaeocarpus ganitrus seeds extract which is a rapid eco-friendly non-chemical Received in revised form way. The prepared NPs were thoroughly analysed by powder x-ray diffraction and high resolution 5 September 2020 transmission electron microscopy studies and were also tested for anticancer studies. Besides the Accepted 8 September 2020 antioxidant antibacterial and anticancer properties of Au NPs were studied. In vitro studies revealed the Available online 22 September 2020 dose-dependent cytotoxic effect of Au NPs. The prepared nanoparticles showed good cytotoxic impact against a prostate cancer PC-3 cells line. The evidences of the current study lead to the synthesis of Keywords Elaeocarpu sganitrus novel and cost-effective drugs from Elaeocarpus ganitrus seeds extract by using the bio approach. Hydrothermal synthesis 2020 The Authors. Publishing services by Elsevier . on behalf of Vietnam National University Hanoi. Gold nanoparticles This is an open access article under the CC BY license http licenses by . Prostate cancer Cancer .