tailieunhanh - Dual targeting of MEK and PI3K efectively controls the proliferation of human EGFR-TKI resistant non-small cell lung carcinoma cell lines with diferent genetic backgrounds

Molecular targeted therapy for non-small cell lung carcinoma (NSCLC) is restricted due to resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). This study evaluated the efects of dual targeting of MEK and PI3K in human EGFR-TKI resistant NSCLC cell lines. |

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