tailieunhanh - Discovering the potential of S. clavuligerus for bioactive compound production: crosstalk between the chromosome and the pSCL4 megaplasmid

Streptomyces clavuligerus ATCC 27064, the industrial producer of the β-lactamase inhibitor clavulanic acid, carries 49 putative secondary metabolite gene clusters. These secondary metabolite gene clusters are distributed between its linear chromosome and the Mb-plasmid pSCL4, a rich reservoir of bioactive compound gene clusters. |

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