tailieunhanh - Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming

Both human and mouse fibroblasts can be reprogrammed to pluripotency with Oct4, Sox2, Klf4, and c-Myc (OSKM) transcription factors. While both systems generate pluripotency, human reprogramming takes considerably longer than mouse. |

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