tailieunhanh - Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene

Optineurin is a gene associated with normal tension glaucoma and amyotrophic lateral sclerosis. It has been reported previously that in cultured RGC5 cells, the turnover of endogenous optineurin involves mainly the ubiquitin-proteasome pathway (UPP). |

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