tailieunhanh - Molecular changes indicative of cartilage degeneration and osteoarthritis development in patients with anterior cruciate ligament injury

Anterior cruciate ligament (ACL) tear is considered a risk factor for osteoarthritis development. The purpose of our study was to investigate the expression levels of the apoptotic enzyme caspase 3, pro-inflammatory cytokines interleukin-1β (IL-1β) and interleukin-6 (IL-6) and degrading enzyme matrix metalloproteinase 13 (MMP-13), all indicative of cartilage degeneration and osteoarthritis development in patients’ chondrocytes after ACL rupture. |