tailieunhanh - FISH Amyloid – a new method for finding amyloidogenic segments in proteins based on site specific co-occurence of aminoacids

Amyloids are proteins capable of forming fibrils whose intramolecular contact sites assume densely packed zipper pattern. Their oligomers can underlie serious diseases, . Alzheimer’s and Parkinson’s diseases. Recent studies show that short segments of aminoacids can be responsible for amyloidogenic properties of a protein. |