tailieunhanh - MADloy: Robust detection of mosaic loss of chromosome Y from genotype‑array‑intensity data

Accurate protocols and methods to robustly detect the mosaic loss of chromosome Y (mLOY) are needed given its reported role in cancer, several age-related disorders and overall male mortality. Intensity SNP-array data have been used to infer mLOY status and to determine its prominent role in male disease. |