tailieunhanh - SciReptor: Analysis of single-cell level immunoglobulin repertoires

The sequencing of immunoglobulin (Ig) transcripts from single B cells yields essential information about Ig heavy: Light chain pairing, which is lost in conventional bulk sequencing experiments. The previously limited throughput of single-cell approaches has recently been overcome by the introduction of multiple next-generation sequencing (NGS)-based platforms. |

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