tailieunhanh - Common molecular mechanism of the hepatic lesion and the cardiac parasympathetic regulation in chronic hepatitis C infection: A critical role for the muscarinic receptor type 3

The pathophysiological overlapping between Sjorgen’s Syndrome (SS) and HCV, presence of antimuscarinic receptor type 3 (M3R) antibodies in SS, the role that M3R plays in the regulation of the heart rate, has led to the assumption that cardiovagal dysfunction in HCV patients is caused by anti-M3R antibodies elicited by HCV proteins or by their direct interaction with M3R. |

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