tailieunhanh - Pluripotency of spermatogonial stem cells injected into mice which were nearly killed by gamma radiation

Spermatogonial stem cells (SSCs) are pluripotent and have properties similar to embryonic stem cells. In this experiment, we collected SSCs from young mouse testis and injected it into mature female mice which were irradiated with gamma rays to bring them to a near death state. | JOURNAL OF SCIENCE OF HNUE Chemical and Biological Sci. 2012 Vol. 57 No. 8 pp. 119-127 This paper is available online at http PLURIPOTENCY OF SPERMATOGONIAL STEM CELLS INJECTED INTO MICE WHICH WERE NEARLY KILLED BY GAMMA RADIATION Nguyen Thi Trung Thu1 Nguyen Lai Thanh2 Vu Dinh Chat2 and Dao Thi Sen1 1 Faculty of Biology Hanoi National University of Education 2 Faculty of Biology University of Science Vietnam National University Abstract. Spermatogonial stem cells SSCs are pluripotent and have properties similar to embryonic stem cells. In this experiment we collected SSCs from young mouse testis and injected it into mature female mice which were irradiated with gamma rays to bring them to a near death state. The mice were irradiated with a dose of 900R to delete marrow hematopoietic stem cells HSCs . SSCs were injected into irradiated mice to determine potential differentiation of SSCs. The result showed that SSCs could prolong the life of the mice and increase the weight of mice that survived the radiation. Upon examination we found cell division and an increase in the number of bone marrow cells. To prove the existence of transplanted SSCs in the irradiated mice we isolated the DNA of some tissues and checked for the presence of Y chromosomes in females. Those organs which most often had SSCs were the heart kidney and bone marrow the liver and brain had the least amount of SSCs. This demonstrates that introduced SSCs divided and differentiated into some types of cells which replaced depleted cells. However further study should be done to determine the potential differentiation of SSCs in irradiated animals. Keywords Spermatogonial stem cells radiated mice gamma ray. 1. Introduction Stem cell technology has improved to open the possibility for new promising medical procedures and interesting results have been obtained in the treatment of Received March 20 2012. Accepted July18 2012. Biology Subject Classification 362 196. Contact Nguyen Thi .

• Sinh học
• Spermatogonial stem cells
• Radiated mice
• Gamma ray
• Chemical and biological
• Hematopoietic stem cells
• In Vitro culture
• Characterization of Spermatogonial stem cells
• Pre pubertal mice
• Groups showed expression
• Different culture systems on the culture of prepuberal buffalo
• The culture of prepuberal buffalo
• Spermatogonial stem cell like cells in vitro
• Stem cell like cells in vitro
• Buffalo SSCs in vitro
• BMC Pediatrics
• Very small embryonic like stem cells
• Peripheral blood circulating stem cells
• Blood testing
• Premature infants
• BMC Cancer
• Hematopoietic stem cell mobilization
• Peripheral blood stem cell transplantation
• Bone marrow
• Non Hodgkin’s lymphoma
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu y khoa
• harrison interal medicine
• Conditioned medium
• Umbilical cord
• Umbilical cord blood
• Mesenchymal stem cells
• Hematopoietic stem cell
• Mesenchymal stem
• Stromal cells
• Progenitor cells capable
• Homogeneous progenitor cell
• Genome Biology
• Chromatin architecture
• Chromosome 11
• Nuclear envelope protein LaminA/C
• The science of stem cells
• Cell differentiation
• Stem cells in the body
• Wound healing and cancer
• Cell differentiation
• The hematopoietic system
• Mesenchymal stromal cells
• Sca 1+MSCs
• Hematopoietic microenvironment
• Antigen presentation ability
• Myelodysplastic syndromes
• Hematopoietic cells
• Acute myeloid leukemia
• Hematopoietic stem cell transplantation
• Graft versus host disease
• Wharton’s jelly
• Peripheral blood stem cells
• Insufficient graft
• Autologous stem cell transplantation
• Multiple myeloma
• immunogenetics
• neuron replacement therapy
• cover hematopoietic
• stem cells
• Cell Research
• Gene Therapy
• báo cáo khoa học
• báo cáo y học
• công trình nghiên cứu về y học
• tài liệu về y học
• cách trình bày báo cáo
• BMC Bioinformatics
• Functional gene set
• Dynamic network biomarker
• Relative effect analysis
• Leukemic stem cell
• AML outcome
• TRPM2 gene expression
• Abnormal myeloid progenitor cells
• BMC Anesthesiology
• Endothelial progenitor cells
• Hypoxia inducible factor 1α
• Stromal cell derived factor 1α
• báo cáo hóa học
• công trình nghiên cứu về hóa học
• tài liệu về hóa học
• Osteogenesis Imperfecta
• Laminopathies
• Progeria Syndrome
• Genetic Determinants
• Heart Rate Variation
• Cardiovascular Diseases