tailieunhanh - ATMAD: Robust image analysis for Automatic Tissue MicroArray De-arraying
We developed a novel de-arraying approach for TMA analysis. By combining wavelet-based detection, active contour segmentation, and thin-plate spline interpolation, our approach is able to handle TMA images with high dynamic, poor signal-to-noise ratio, complex background and non-linear deformation of TMA grid. |
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