tailieunhanh - Exome profiling of primary, metastatic and recurrent ovarian carcinomas in a BRCA1-positive patient

Ovarian carcinoma is a common, and often deadly, gynecological cancer. Mutations in BRCA1 and BRCA2 genes are present in at least a fifth of patients. Uncovering other genes that become mutated subsequent to BRCA1/BRCA2 inactivation during cancer development will be helpful for more effective treatments. |

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