tailieunhanh - Negative transcriptional control of ERBB2 gene by MBP-1 and HDAC1: Diagnostic implications in breast cancer

The human ERBB2 gene is frequently amplified in breast tumors, and its high expression is associated with poor prognosis. We previously reported a significant inverse correlation between Myc promoter-binding protein-1 (MBP-1) and ERBB2 expression in primary breast invasive ductal carcinoma (IDC). |

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