tailieunhanh - Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) diagnosed within the first month of life is classified as congenital ALL and has a significantly worse outcome than ALL diagnosed in older children. This suggests that congenital ALL is a biologically different disease, and thus may be caused by a distinct set of mutations. |

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