tailieunhanh - Salinomycin increases chemosensitivity to the effects of doxorubicin in soft tissue sarcomas

Chemotherapy for soft tissue sarcomas remains unsatisfactory due to their low chemosensitivity. Even the first line chemotherapeutic agent doxorubicin only yields a response rate of 18-29%. The antibiotic salinomycin, a potassium ionophore, has recently been shown to be a potent compound to deplete chemoresistant cells like cancer stem like cells (CSC) in adenocarcinomas. |

TÀI LIỆU LIÊN QUAN
TỪ KHÓA LIÊN QUAN