tailieunhanh - SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells

SMAD4 is a gastrointestinal malignancy-specific tumor suppressor gene found mutated in one third of colorectal cancer specimens and half of pancreatic tumors. SMAD4 inactivation by allelic deletion or intragenic mutation mainly occurs in the late stage of human pancreatic ductal adenocarcinoma (PDAC). |

TÀI LIỆU LIÊN QUAN
TỪ KHÓA LIÊN QUAN