tailieunhanh - Dexamethasone for the prevention of a pain flare after palliative radiotherapy for painful bone metastases: A multicenter double-blind placebo-controlled randomized trial

Radiotherapy has a good effect in palliation of painful bone metastases, with a pain response rate of more than 60%. However, shortly after treatment, in approximately 40% of patients a temporary pain flare occurs, which is defined as a two-point increase of the worst pain score on an 11-point rating scale compared to baseline, without a decrease in analgesic intake, or a 25% increase in analgesic intake without a decrease in worst pain score, compared to baseline. |

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