tailieunhanh - Effect of gastrointestinal resection on sunitinib exposure in patients with GIST

GIST patients often undergo GI-surgery. Previous studies have shown that imatinib and nilotinib exposures were decreased in GIST patients with prior major gastrectomy. We investigated whether major gastrectomy influences the exposure to sunitinib and its active metabolite SU12662. |

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