tailieunhanh - Modification of topoisomerases in mammospheres derived from breast cancer cell line: Clinical implications for combined treatments with tyrosine kinase inhibitors

Accumulating evidences suggest that tumors are driven by a small population of cells, termed “cancer stem cells” (CSCs), which may be resistant to current therapeutic approaches. In breast carcinoma, the CSCs have been identified as a CD44+ /CD24− cell population. |

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