tailieunhanh - NPC1L1 knockout protects against colitis-associated tumorigenesis in mice

Colorectal cancer is strongly associated with lipid metabolism. NPC1L1, a sterol transporter, plays a key role in modulating lipid homeostasis in vivo. Its inhibitor, ezetimibe, began to be used clinically to lower cholesterol and this caused the great debate on its role in causing carcinogenesis. Here we explored the role of NPC1L1 in colorectal tumorigenesis. |

TÀI LIỆU LIÊN QUAN
TỪ KHÓA LIÊN QUAN