tailieunhanh - The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARαtr, autonomously regulates proliferative and pro-inflammatory genes

The peroxisome proliferator-activated receptor alpha (PPARα) controls lipid/energy homeostasis and inflammatory responses. The truncated splice variant PPARα-tr was suggested to exert a dominant negative function despite being unable to bind consensus PPARα DNA response elements. |

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