tailieunhanh - UBR-box containing protein, UBR5, is overexpressed in human lung adenocarcinoma and is a potential therapeutic target

N-end rule ubiquitination pathway is known to be disrupted in many diseases, including cancer. UBR5, an E3 ubiquitin ligase, is mutated and/or overexpressed in human lung cancer cells suggesting its pathological role in cancer. |

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