tailieunhanh - Evaluation of BRCA1-related molecular features and microRNAs as prognostic factors for triple negative breast cancers

The BRCA1 gene plays a key role in triple negative breast cancers (TNBCs), in which its expression can be lost by multiple mechanisms: Germinal mutation followed by deletion of the second allele; negative regulation by promoter methylation; or miRNA-mediated silencing. |

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