tailieunhanh - 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response

The Her2 receptor is overexpressed in up to 25 % of breast cancers and is associated with a poor prognosis. Around half of Her2+ breast cancers also express the estrogen receptor and treatment for such tumours can involve both endocrine and Her2-targeted therapies. |

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