tailieunhanh - Combining genomic analyses with tumourderived slice cultures for the characterization of an EGFR-activating kinase mutation in a case of glioblastoma

Epidermal growth factor receptor (EGFR) gene alterations and amplification are frequently reported in cases of glioblastoma (GBM). However, EGFR-activating mutations that confer proven sensitivity to tyrosine kinase inhibitors (TKIs) in lung cancer have not yet been reported in GBM. | Combining genomic analyses with tumourderived slice cultures for the characterization of an EGFR-activating kinase mutation in a case of glioblastoma

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