tailieunhanh - Immune targeting of autocrine IGF2 hampers rhabdomyosarcoma growth and metastasis

Insulin-like Growth Factor Receptor-1 (IGF1R) system sustains the genesis of rhabdomyosarcoma through IGF2 autocrine overexpression. While several IGF1R-targeted strategies have been investigated to interphere with rhabdomyosarcoma growth, no attempt to neutralize IGF2 has been reported. | Immune targeting of autocrine IGF2 hampers rhabdomyosarcoma growth and metastasis

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