tailieunhanh - S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes

The secretion of soluble factors enables communication between tumour cells and the surrounding microenvironment and plays an important role in oncogenesis. Pancreatic ductal adenocarcinoma (PDAC) is characterised by a highly reactive microenvironment, harbouring a variety of cell types, including S100A8/ S100A9-expressing monocytes. | S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes

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