tailieunhanh - Cytology material is equivalent to tumor tissue in determining mutations of BRCA 1/2 genes in patients with tubo-ovarian high grade serous carcinoma

High-grade serous ovarian cancer is a detrimental disease. Treatment options in patients with a recurrent disease are dependent on BRCA1/2 mutation status since only patients with known BRCA mutation are eligible for treatment with poly(ADP-ribose) polymerase inhibitors (PARPi). | Cytology material is equivalent to tumor tissue in determining mutations of BRCA 1 2 genes in patients with tubo-ovarian high grade serous carcinoma

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