tailieunhanh - Synthesis and evaluation of gyps vulture multidrug resistant protein 4 (MRP4/ABCC4) specific multiple antigenic peptide (MAP) for its immunoreactivity

Efforts are in progress to conserve critically endangered Gyps spp. vultures by identifying and removing the vulture-unsafe drugs from the food chain. Several drugs namely diclofenac, aceclofenac, ketoprofen and nimesulide are found to cause hyperuricemia and fatal nephrotoxicity in Gyps vultures. Research on development of an in vitro model for screening drugs in practice and the new molecules for their hyperuricemic potential can facilitate the conservation efforts. | Synthesis and evaluation of gyps vulture multidrug resistant protein 4 MRP4 ABCC4 specific multiple antigenic peptide MAP for its immunoreactivity